Diagnosed with SMM, SPB, or MGUS?

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MGUS- monoclonal gammopathy of undetermined significance

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Monoclonal Gammopathy of Undetermined Significance aka MGUS is not cancer. It is considered to be a “blood disorder” or pre-multiple myeloma.

Hello David: Great work you are doing to get us informed! I received an MGUS diagnosis (Monoclonal Gammopathy of Undermined Significance)  in 2016.

I’m a 66 yr. old female, 5’3″, 115-119 lbs. My diet for the last 20 yrs. or so has been fairly clean ( at times I slip off the wagon with either gluten, sugar, dairy or non organic). Otherwise:

  • I drink filtered water (Big Berkey),
  • I juice greens, carrots, beets, ginger root, turmeric root, and
  • purchase as much local organic farm vegetables as possible and eat wild edibles (when available).

I’m on a few supplements:

  • vitamin D3,
  • Chaga tincture and sometimes chaga tea,
  • Vitamin B12, sublingual,
  • Curumin on occasion,
  • vitamin C on occasion tablet form  

Every week or so I’ll make white cedar tea, or white pine needle tea and broccoli sprouts on occasion. I drink grass fed protein powder a few times/week.

My complementary therapies are as follows:

  • Very little to no toxic skin care products.
  • Walking 30 min. 3-5 times/week.
  • Hydrotherapy in the shower.
  • I use an infrared Dome at home daily for a few hrs/day.
  • I take CBD oil and THC oil and 1-2 puffs of dried THC at night only for sleep.
  • One registered massage therapy session/month.

I have blood work once/yr and so far all is stable. I worry most of the time about this MGUS progressing. It’s on my mind most days which I know is not the best way to live. I stress easily.

Are you able to calm my minds thinking in any way with your knowledge? I am really against conventional cancer treatments. Also, I’m not on any medical prescriptions except for the cannabis. Your thoughts would be much appreciated. Phoebe

Hi Phoebe-

The best way for me to calm your mind relative to an MGUS diagnosis is to cite statistics as well as my experience.

Your risk of progressing from MGUS to full-blown MM is 1% per year. Your diet, supplementation and lifestyle therapies all reduce this annual risk. Therefore, my belief is that your annual risk of your MGUS progressing to MM is LESS than 1% a year.

If you do progress to MM, by “PRE-habilitating” (diet, supplements, lifestyle), again, according to research, you will respond to chemotherapy very well. Therefore your prognosis as a person diagnosed with early stage MM is excellent.

For the record, I too fall of the wagon occasionally where my anti-MM diet is concerned. I too think about a possible MM relapse, treatment related secondary cancer, etc. frequently (daily…).

As the study linked below and “recommended reading” indicates, there are risks in life…of many different types of health challenges. You are doing most everything you can to reduce your risks of MGUS progressing to multiple myeloma.

My point is that we both are doing well.

Hang in there,

David Emerson

  • MM Survivor
  • MM Coach
  • Director PeopleBeatingCancer 

Recommended Reading:

Pesticide exposure and risk of monoclonal gammopathy of undetermined significance in the Agricultural Health Study.

“Pesticides are associated with excess risk of multiple myeloma, albeit inconclusively.

We included 678 men (30-94 years) from a well-characterized prospective cohort of restricted-use pesticide applicators to assess the risk of monoclonal gammopathy of undetermined significance (MGUS). Serum samples from all subjects were analyzed by electrophoresis performed on agarose gel; samples with a discrete or localized band were subjected to immunofixation. Age-adjusted prevalence estimates of MGUS were compared with MGUS prevalence in 9469 men from Minnesota.

Associations between pesticide exposures and MGUS prevalence were assessed by logistic regression models adjusted for age and education level. Among study participants older than 50 years (n = 555), 38 were found to have MGUS, yielding a prevalence of 6.8% (95% CI, 5.0%-9.3%).

Compared with men from Minnesota, the age-adjusted prevalence of MGUS was 1.9-fold (95% CI, 1.3- to 2.7-fold) higher among male pesticide applicators. Among applicators, a 5.6-fold (95% CI, 1.9- to 16.6-fold), 3.9-fold (95% CI, 1.5- to 10.0-fold), and 2.4-fold (95% CI, 1.1- to 5.3-fold) increased risk of MGUS prevalence was observed among users of the chlorinated insecticide dieldrin, the fumigant mixture carbon-tetrachloride/carbon disulfide, and the fungicide chlorothalonil, respectively.

In summary, the prevalence of MGUS among pesticide applicators was twice that in a population-based sample of men from Minnesota, adding support to the hypothesis that specific pesticides are causatively linked to myelomagenesis.”

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