You’ve been diagnosed with monoclonal gammopathy of undetermined significance (MGUS) and you are trying to wrap your brain around this diagnosis. It is an asymptomatic “blood disorder” yet it can become a full-blown diagnosis of an incurable blood cancer called multiple myeloma.
My experience as a long-term cancer survivor is that the more you the patient, learn about your diagnosis, the more in control you will become.
Click the mind map below to learn more about MGUS-
This may sound odd but from my perspective you are in a kind of a cancer sweet spot. By this I mean that your diagnosis should motivate you to make an effort to remain PRE-MM. And you can be certain you are pre-MM or MGUS only through diagnostic testing your blood, marrow and bones.
MGUS at a glance-
Frankly, regular testing is a small price to pay considering the downside risks of your monoclonal gammopathy of undetermined significance becoming Multiple Myeloma. The diagnostic testing linked below will explanation of some of the tests you will have short and/or long term.
If you do not want to “watch and wait” to see if your pre-MM progresse to Multiple Myeloma scroll down the page, post a question or a comment and I will reply to you ASAP.
Consider monoclonal gammopathy of undetermined significance Therapies such as:
To learn more about these MGUS therapies, please watch the short video below:
“MGUS is usually detected during blood tests for another condition, such as a certain nerve disorder (peripheral neuropathy). The blood tests can show abnormal proteins as well as unusual amounts of normal proteins. If your doctor detects monoclonal gammopathy, further testing may be recommended to determine which M protein your body is making and how much is being made…”
“Serum protein electrophoresis (SPEP) is an easy, inexpensive method of separating proteins based on their net charge, size, and shape…”
“Immunoglobulin light chains that are circulating in serum in a free (unbound) state are called free light chains (FLCs). Measurement of the serum level of FLCs became practical as a clinical blood test in recent decades..”
“Multiple myeloma is the most common primary malignant neoplasm of the skeletal system. The disease is a malignancy of plasma cells. Clinical definitions of the various myeloma subtypes have been updated as have the imaging definitions of what constitutes bone marrow disease and individual bony involvement..”
“Our findings suggest that reports on bone biopsies should include in addition to the number of plasma cells, the pattern of plasma cell infiltration and the presence or absence of multiple lymphoid nodules…”