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Smoldering multiple myeloma (SMM) is an early precursor to a rare blood cancer known as multiple myeloma, which affects plasma cells. This type of cancer produces certain proteins that can be measured in both blood and urine. These proteins show up before a person has any symptoms of cancer…
Multiple myeloma, like other cancers, can be defined by stages. There are three stages of the disease, each more advanced than the one before. A precursor to stage 1 is known as SMM.
A person can have SMM for several years before they progress to stage 1 multiple myeloma. Even when there are no outward symptoms, the malignant plasma cells secrete proteins into the body. These proteins can be measured in the blood or urine of people who otherwise exhibit no signs of disease.
There may be lesions on the spines of people with SMM. One studyTrusted Source showed that monitoring these tumors regularly with MRI scans can detect the progression of the disease…”