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According to research linked and excerpted below, collagen (col) benefits from vitamin D to enhance skin, bone, and hopefully, my heart.
I am a long-term cancer survivor. I developed a late stage side effect called chemotherapy-induced cardiomyopathy fully 15 years after I underwent the various chemotherapies that damaged my heart.
When I first flipped into chronic atrial fibrillation (afib), I was prescribed a conventional heart medicine called metoprolol. I experienced nasty side effects and decided to try to manage my heart with evidence-based non-conventional therapies.
I’ve been taking collagen as well as a dozen other supplements shown to enhance heart health for years now. I recently found the studies linked below that talk about the importance of adding vitamin D with collagen.
Collagen is a protein that makes up a significant portion of our skin, hair, nails, joints, and connective tissues. It plays a crucial role in maintaining the structural integrity of these tissues. Collagen supplementation has gained popularity in recent years, and some potential physical benefits include:
I don’t mean to come across as being anti-conventional heart therapies. As a long-term cancer survivor, I’ve learned that evidence-based non-conventional therapies can complement conventional therapies to benefit the patient.
Are you a cancer survivor? Do you have chemotherapy-induced cardiomyopathy? Let me know- David.PeopleBeatingCancer@gmail.com
Hang in there,
“Col is the main load bearing protein in many soft tissues, and in cardiovascular tissues in particular. In many tissues col has a specific architecture that is crucial for the biomechanical function of the tissue. Typical examples are the hammock-shaped col architecture in heart valves and a helical pattern in arteries. One of the objectives in cardiovascular tissue engineering is the reconstitution of this architecture…”
“The interplay between vitamin D, the renin–angiotensin system (RAS), and collagen remodeling has been implicated in the pathogenesis of various cardiovascular diseases.
This study sought to explore this relationship in atrial fibrillation (AF) by profiling plasma levels of 25-hydroxyvitamin D, RAS biomarkers, and col remodeling biomarkers using the enzyme-linked immunosorbent assay method.
We hypothesized that 25-hydroxyvitamin D levels would inversely correlate with RAS biomarkers and that levels of RAS and col remodeling biomarkers would positively correlate with each other.
These data suggest that 25-hydroxyvitamin D may influence RAS activation, and renin may help mediate the col remodeling process in AF. Understanding mediators of RAS dysregulation in AF may elucidate targets for therapeutic intervention to prevent col remodeling…”
Conclusion- Renin and CITP elevations suggest that RAS and col remodeling may be involved in the pathogenesis of AF. Although our data do not suggest the idea that 25-hydroxyvitamin D deficiency is associated with AF, it does demonstrate that 25-hydroxyvitamin D and renin have an inverse relationship in patients with AF. Additionally, renin may be an important mediator in the col dysregulation based on its positive correlations with col remodeling biomarkers…”