Chronic systemic inflammation becomes increasingly associated with risk of death, loss of cognitive function and increasing dependency
Could the progression of pre-MM (SBP, MGUS, SMM) be slowed or even halted by reducing inflammation? Could five nutritional supplements reduce inflammation? I added each of the five supplements to my diet as I came upon anti-myeloma research for this website and my own learning as a long-term survivor of an “incurable” blood cancer.
I came to learn that reducing inflammationis critical in reducing my risk of a secondary cancer but also in reducing my risk of many chronic diseases including Alzheimer’s Disease.
It follows then, that reducing inflammation reduces the risk of pre-myeloma becoming full-blown myeloma, right?
These five supplements listed below are part of my diet and I recommend that you supplement with them as well. For the record I exercise frequently but moderately, I drink a glass of wine a few times a week and I eat a lot of fruits and veggies.
Is it coincidence that five of the most effective nutrition supplements to reduce your risk of cancers and other chronic diseases are the same five supplements that also reduce inflammation in your body? Considering the study linked and excerpted below, is also coincidence that inflammation is the best predictor of successful aging?
I am a long-term survivor of an “incurable cancer” called multiple myeloma. I’ve lived through aggressive conventional/traditional chemotherapy and radiation only to “fail” and told I was terminal. I pursued a controversial alternative medicine and achieved complete remission status in early ’99 where I remain to this day.
I supplement with the five nutritional, anti-oxidant, anti-inflammatory supplements below. I have no idea how long I’ll live obviously but I will admit that I enjoyed finding and reading the study linked below.
Let me be clear. I am not saying that nutritional supplementation will cure cancer. I am saying that my anti-MM lifestyle helps be remain MM free.
The Pre-MM Cancer Coaching Program is based on years of research and writing about both pre and full MM. Scroll down the page to learn more about the Pre-MM CC Program.
Check back with me every decade or so and you can find out how I’m doing.
“Multiple myeloma is an invariably fatal cancer of plasma cells. Despite tremendous advances in treatment, this malignancy remains incurable in most individuals.
We postulate that strategies aimed at prevention have the potential to be more effective in preventing myeloma-related death than additional pharmaceutical strategies aimed at treating advanced disease. Here, we present a rationale for the development of prevention therapy and highlight potential target areas of study…
Obesity and Inflammation
We previously reviewed the literature linking obesity with the progression of multiple myeloma [55] and much attention has been given to understanding the mechanism that link these two pathologies. One of the largest prospective studies to evaluate obesity and cancer risk clearly demonstrates an increased risk of myeloma death (relative risk = 1.44) in men and women in with a body mass index of 30–34.9 kg/m2 [54]. Obesity is additionally linked with an increased risk of MGUS…
Vitamin Deficiency
… In MGUS patients, Vitamin D supplementation improves markers of bone health and metabolism [98]. Given the low risk profile of Vitamin D supplemental, and the general recommendation, the Vitamin D deficient patients take a supplement, this is potential treatment option [98]…
Conclusions
In order to move towards clinical trials in myeloma prevention, we need more research on the basic biology underlying the transition from premalignant to malignant myeloma. The goal of this review is not to change current management at this time, but to raise awareness for the concept of disease prevention in multiple myeloma. Our laboratory is interested in the relationship between obesity, sleep apnea, and myeloma pathophysiology and we feel this deserves closer study. Finally, it is important for healthcare providers to comprehensively evaluate the financial costs of current myeloma treatments at their institutions in order to justify the cost of prevention strategies.”
We identify potential drivers of multiple dimensions of the ageing process up to 110 years of age.
Inflammation is the prime candidate amongst potential determinants of mortality, capability and cognition up to extreme old age.
Telomere length does not predict successful ageing in the very and extreme old, but centenarians and their offspring maintain telomeres better than non-centenarians.
Centenarians are less susceptible to the diseases, functional losses and dependencies of old age than the general public. Why centenarians age differently, i.e. which biological and pathophysiological processes drive ageing at this extreme old age, is not known. We found that chronic systemic inflammation becomes increasingly associated with risk of death, loss of cognitive function and increasing dependency, but did not predict multimorbidity. In contrast, long telomeres might be important to become a centenarian but did not predict the ageing process further on. Suppression of chronic inflammation could be an essential step towards further improvements in human healthy lifespan.”
“According to ConsumerLabs.com optimal blood levels of vitamin D3 may prevent cancer, enhance bone health, reduce the risk of Parkinson’s, rheumatoid arthritis, heart attacks, diabetes, hypertension, reduce symptoms of fibromyalgia, reduce the risk uterine fibroids, Alzheimer’sdisease, dementia, depression, and other conditions.”
“Curcumin as nutritional supplement may help treat cancer, inflammation, ulcerative colitis, rheumatoid arthritis, osteo arthritis, diabetes, depression, anxiety, cognitive function and fatigue, chronic anterior uveitis and other conditions.”
“Resveritrol supplementation may treat cancer, may lower bad cholesterol, may reduce levels of inflammation, improves insulin sensitivity in diabetics, may help memory function and may help prevent the onset of Alzheimer’s Disease dementia and other neurodegenerative disorders.”
regular green tea consumption is associated with 20% less risk of coronary artery disease as well as a reduced risk of death caused by heart disease–
consumption of three or more cups of green tea daily reduces risk of ischemic stroke by 21%
regular consumption of green tea reduced the risk of many cancers including prostate, breast and lung cancers-
may decrease the risk of developing type 2 diabetes–
laboratory research has suggested a role of green tea extracts in shrinking uterine fibroids–
higher consumption of green tea has been associated with a lower prevalence of cognitive impairment in older adults-
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