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Autologus peripheral blood stem cell transplantation (ASCT) is aggressive, high-dose chemotherapy. Central to ASCT is collecting enough of one’s own stem cells to properly re-populate one’s immune system after undergoing high-dose chemotherapy. HBOT is an important multiple myeloma therapy because it is an unconventional therapy that can be essential to a patient who needs to increase his/her stem cell production.
It is common to have more than one ASCT and therefore patients often need to collect enough stem cells for multiple stem cell transplants.
I participate in many online cancer platforms. Peripheral blood stem cell transplants are frequently discussed. The majority of the discussion is how well they work for multiple myeloma. There is also discussion of doing two transplants- a tandem transplant.
Occasionally posters will refer to their ability to collect their own stem cells. Some have no problem collecting their stem cells and many do not collect enough stem cells. When you have plenty of stem cells for collection it seems as if the collection process is a breeze.
As the two articles linked below illustrate, hyperbaric oxygen therapy can improve stem cell collection.
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“The actual treatments (HBOT treatments) were easy. He said that his ears would feel pressure, like while flying in an airplane. The chamber was clear, and he could watch TV during his 90 minute sessions…
Dave’s WBC count jumped from below 2.0 to over 13 during the night! They ran the ProCOUNT test, and Dave’s was at 50 million cells available for collection! The collection doctor said that in 20 years of doing this she had never seen anyone with his extensive radiation history with those numbers!”
“According to a study to be published in the American Journal of Physiology-Heart and Circulation Physiology, a typical course of hyperbaric oxygen treatments increases by eight-fold the number of stem cells circulating in a patient’s body. Stem cells, also called progenitor cells are crucial to injury repair. The study currently appears on-line and is scheduled for publication in the April 2006 edition of the American Journal…
“This is the safest way clinically to increase stem cell circulation, far safer than any of the pharmaceutical options,” said Stephen Thom, MD, Ph.D., Professor of Emergency Medicine at the University of Pennsylvania School of Medicine and lead author of the study. “This study provides information on the fundamental mechanisms for hyperbaric oxygen and offers a new theoretical therapeutic option for mobilizing stem cells.””