Numerous studies correlate the importance of Vitamin D3 with numerous chronic diseases. Cancer in particular. Or should I say that low blood levels of vitamin D3 are associated with many diseases? Cancer in particular.
As a cancer survivor and cancer coach, I believe that the issue is not how much vitamin D3 to take. Dosing won’t tell you what you need to know about your serum blood levels of vitamin D3.
The trick is to learn about what your individual serum blood Vitamin D3 level is.
I live in Cleveland, Ohio. I am a cancer survivor who has a long-term risk of melanoma. I stay out of the sun. Therefore, I need to supplement with Vitamin D3.The numbers listed below are taken from LabCorp blood testing in 2009. 2011 and 2014.
I take Life Extension Vitamin D3 because this brand has been tested and approved by ConsumerLab.com an independent testing service. I encourage you to have your blood checked for Vitamin D3 and, depending on your results, supplement with Vitamin D3 .
Vitamin D, 25-Hydroxy 36.9 ng/mL 32.0-100.0
Vitamin D, 25-Hydroxy 38.8 ng/mL 32.0-100.0
Vitamin D, 25-Hydroxy 31.9 ng/mL 30.0-100.0
“Elevated 25-hydroxyvitamin D concentrations are inversely correlated with cancer risk, according to a study published in the BMJ…
The primary outcome was the incidence of overall or specific cancer. The investigators selected 4044 random subgroup volunteers to match the 3301 cancer patients and measured the concentration of plasma 25-hydroxyvitamin D with an enzyme immunoassay.
Participants were sorted into quarters based on gender- and season-specific distributions of 25-hydroxyvitamin D, and hazard models were calculated using statistical analysis. Of the separated groups, the lowest quarter was used as the reference.
The researchers reported that increased circulating 25-hydroxyvitamin D concentrations were negatively correlated with total cancer risks for the second, third, and fourth quarter groups. Using the first quarter’s multivariable-adjusted hazard ratio (HR) as the reference, the investigators found that the second, third, and fourth quarters resulted in a reduced risk for cancer (HR, 0.81, 0.75, and 0.78, respectively)…”
“CONCLUSIONS: In this large cohort study, serum 25(OH)D concentrations were inversely associated with all-cause and cause-specific mortality. In particular, vitamin D deficiency [25(OH)D concentration <30 nmol/L] was strongly associated with mortality from all causes, cardiovascular diseases, cancer, and respiratory diseases.
Fact Sheet for Health Professionals
“Vitamin D is a fat-soluble vitamin that is naturally present in very few foods, added to others, and available as a dietary supplement. It is also produced endogenously when ultraviolet rays from sunlight strike the skin and trigger vitamin D synthesis….
Serum concentration of 25(OH)D is the best indicator of vitamin D status…
Based on its review of data of vitamin D needs, a committee of the Institute of Medicine concluded that persons are at risk of vitamin D deficiency at serum 25(OH)D concentrations <30 nmol/L (<12 ng/mL). Some are potentially at risk for inadequacy at levels ranging from 30–50 nmol/L (12–20 ng/mL). Practically all people are sufficient at levels ≥50 nmol/L (≥20 ng/mL); the committee stated that 50 nmol/L is the serum 25(OH)D level that covers the needs of 97.5% of the population. Serum concentrations >125 nmol/L (>50 ng/mL) are associated with potential adverse effects  (Table 1).”
“Relative to participants with a concentration of 50 nmol/L, participants with less than 25 nmol/L had approximately 20% higher odds of RCC. Correspondingly, participants with concentrations greater than 100 nmol/L had 20% lower odds of RCC relative to those with a concentration of 50 nmol/L, but very few participants had concentrations as high as 100 nmol/L.”
“Patients who have genetically low vitamin D appear to be at an increased risk of premature death, according to a mendelian randomization study reported in BMJ…