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Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission

Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.

Click the orange button to the right to learn more about what you can start doing today.

Cannabidiol Kills Multiple Myeloma, Enhances Chemo

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Multiple Myeloma Patients and Survivors Must Use the Best of Both Conventional and Non-Conventional Therapies to Treat their Incurable Blood Cancer-

Multiple myeloma (MM) patients are often told that their cancer is incurable but very treatable.” When I was first diagnosed with multiple myeloma I found this statement to be confusing.  When I found a study showing that cannabidiol kills myeloma and enhances Velcade, I understood how MM could be incurable but treatable.

The study linked and excerpted below is an excellent example of how multiple myeloma is incurable but treatable. Your oncologist will admit that Velcade (bortezomib) will eventually stop working. But cannabidiol is cytotoxic to MM and it enhances the efficacy of Velcade.

 

Cannabidiol causes your MM to be more sensitive to Velcade.  More importantly, there are many other evidence-based, non-toxic therapies that also make your MM more sensitive to Velcade.

Myeloma is about two things:

  1. symptoms (bone damage, anemia, kidney function, etc.) resulting from your disease
  2. side effects of toxic chemotherapy.

MMers usually don’t die from their cancer. They die from health problems caused by their cancer such as bone damage and/or from the toxicity caused by chemotherapy and radiation.

The solution? Take an integrative approach to managing your multiple myeloma. Enhance the efficacy of chemotherapy and while you reduce the toxicity. I live an anti-MM lifestyle based on nutrition, supplementation, lifestyle, bone health and mind-body therapies.

If you’d like to learn more about the following topics from an evidence-based perspective, please click the blue button below to register for a FREE webinar:

    1. Listing of the most successful MM specialists and hospitals
    2. Dozens of foods that starve MM (anti-MM) foods
    3. 15 integrative therapies that synergize with five common MM chemotherapy regimens,
    4. Over a dozen evidence-based mind-body therapies,
    5. Detoxification therapies,
    6. Both conventional and non-conventional bone health therapies
    7. Review and links to more than 20 online MM support groups
    8. Studies reviewing Cannabis as integrative MM therapy, pain therapy and stand-alone MM therapy

Thank you,

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:


The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. A role for transient receptor potential vanilloid type-2.

“Because bortezomib (BORT) (Velcade) is commonly used in MM treatment, we investigated the effects of Cannabidiol and BORT in CD138+TRPV2- MM cells and in MM cell lines transfected with TRPV2 (CD138+TRPV2+). 

These results showed that Cannabidiol by itself or in synergy with BORT strongly inhibited growth, arrested cell cycle progression and induced MM cells death by regulating the ERK, AKT and NF-κB pathways with major effects in TRPV2+ cells. These data provide a rationale for using Cannabidiol to increase the activity of proteasome inhibitors in MM.”


Multiple Myeloma Pain Management- Cannabinoids, C-B-D

Cannabinoids treat myeloma pain, combat treatment-related nausea, produce apoptosis, inhibit cancer-induced angiogenesis, and inhibit cachexia-

 While the legalization of Medical Marijuana/Cannabidiol, C-B-D continues to be debated state by state, one thing is clear. Medical marijuana, cannabinoids, C-B-D can help manage multiple myeloma pain. More importantly, studies document the ability of C-B-D to enhance the efficacy of specific myeloma therapies.
 The ongoing challenge to MM patients searching for solid information about C-B-D and its effect on pain is that there will be limited research in the US as long medical marijuana is classified as a schedule one drug.
Common questions from MM patients are 1) C-B-D vs. THC, one or the other or both? 2) Dosing aka how much do I take? and 3) what type, strain, etc. What do I ask for?

I am both a MM survivor and MM cancer coach. Personal experience and working with myeloma patients has taught me that collateral damage aka side effects are just as much of a concern as the multiple myeloma itself it. Are you experiencing cancer pain in any form?

For more information about cancer pain management, scroll down the page, post a question or comment and I will reply ASAP.


Recommended Reading:


A selective review of medical cannabis in cancer pain management

” Insufficient management of cancer-associated chronic and neuropathic pain adversely affects patient quality of life. Patients who do not respond well to opioid analgesics, or have severe side effects from the use of traditional analgesics are in need of alternative therapeutic options. Anecdotal evidence suggests that medical cannabis has potential to effectively manage pain in this patient population.

This review presents a selection of representative clinical studies, from small pilot studies conducted in 1975, to double-blind placebo-controlled trials conducted in 2014 that evaluated the efficacy of cannabinoid-based therapies containing tetrahydrocannabinol (THC) and cannabidiol (CBD) for reducing cancer-associated pain.

… A variety of doses ranging from 2.7–43.2 mg/day THC and 0–40 mg/day CBD were administered. Higher doses of THC were correlated with increased pain relief in some studies. One study found that significant pain relief was achieved in doses as low as 2.7–10.8 mg THC in combination with 2.5–10.0 mg CBD, but there was conflicting evidence on whether higher doses provide superior pain relief. Some reported side effects include drowsiness, hypotension, mental clouding, and nausea and vomiting. There is evidence suggesting that medical cannabis reduces chronic or neuropathic pain in advanced cancer patients. However, the results of many studies lacked statistical power, in some cases due to the limited number of study subjects. Therefore, there is a need for the conduct of further double-blind, placebo-controlled clinical trials with large sample sizes in order to establish the optimal dosage and efficacy of different cannabis-based therapies…

Conclusions- Current research shows that there is a potential role for medical cannabis in cancer pain management. However, the scale and quality of studies conducted to date are somewhat limited (12). Therefore, further research is needed to establish the efficacy of medical cannabis, either as an alternative to opiates or as an adjunctive therapy, and to identify the most appropriate methods of administration to achieve optimal therapeutic efficacy with minimal side effects.”

Medical Cannabis Found to Safely Reduce Chronic Pain in Older Patients in Study

“Medical cannabis was found to safely and significantly reduce chronic pain in older patients with multiple sclerosis (MS) and a wide range of other conditions, researchers in Israel report…

Researchers evaluated the safety and efficacy of treating older adults, ages 65 and above — a growing patient population — with medical cannabis. The study included 2,736 patients with a mean age of 74.5, who received medical cannabis from January 2015 to October 2017 at a specialized clinic and agreed to answer a questionnaire.

The group included people with MS, Parkinson’s disease, cancer, post-traumatic stress disorder (PTSD), ulcerative colitis, and Crohn’s disease. Most were prescribed cannabis treatment for pain, particularly that due to cancer and its treatments.

More than 33 percent used cannabis-infused oil, about 24 percent inhaled or smoked the cannabis, and around 6 percent used vaporization.

Data showed that after six months of medical cannabis treatment, the vast majority of patients reported moderate to significant improvements in their condition, with more than 93.7 percent — of 901 respondents — reporting a significant decrease in pain levels (declining from a median of eight on a 10-point scale to four). Approximately 60 percent of these respondents also reported an improved quality of life…”

Cannabinoids in the management of difficult to treat pain

“Cannabinoids may offer significant “side benefits” beyond analgesia. These include anti-emetic effects, well established with THC, but additionally demonstrated for CBD (Pertwee 2005), the ability of THC and CBD to produce apoptosis in malignant cells and inhibit cancer-induced angiogenesis (Kogan 2005; Ligresti et al 2006), as well as the neuroprotective antioxidant properties of the two substances (Hampson et al 1998), and improvements in symptomatic insomnia (Russo et al 2007)…”

Cannabinoid Shown Effective as Adjuvant Analgesic for Cancer Pain

“While opioid therapy is the mainstay treatment for cancer pain in patients with advanced disease, a substantial minority experience pain that cannot be adequately controlled at safe and tolerable doses. The most common treatment approach is co-administration of another analgesic. Cannabinoids are being analyzed as potential adjuvant analgesics…

Patients were eligible to participate in the study if they had active cancer and chronic pain that was moderate to severe despite taking opioids…Results of the study showed that nabiximols have analgesic efficacy when used as an add-on therapy for cancer patients with pain not controlled by an opioid alone. In the low-dose nabiximols group, there was a 25 percent improvement in pain compared with baseline.”

Marijuana Component Could Ease Pain from Chemotherapy Drugs, Study Suggests

“The researchers developed animal models and tested the ability of the compound cannabidiol, which is the second most abundant chemical found in the marijuana plant, to relieve chemo-induced neuropathic pain…We found that cannabidiol completely prevented the onset of the neuropathic, or nerve pain caused by the chemo drug Paclitaxel, which is used to treat breast cancer..

 

 

 

Leave a Comment:

36 comments
tim warden says 7 months ago

What brand CBD oil do you recommend

Reply
Robert Stoton says 7 months ago

Diagnosed sept 2017 high risk t4,14 stage III (was close to death had hemoglobin of less than 50)used velcade triplets with rso(full cannabis plant extract) dropped chemo altogether March 2018. Dropped RSO a little later.
M spike returned Nov 2019 been using 300 mg full plant extract thc and 200-300mg full plant extract cbd 200mg since then, daily. The thc you have to build up a tolerance, one gram of oil is way more potent than smoking 7 grams all in one joint (I take the oil under my tongue the thc I take in the early evening) Indica strains tend to make you sleep were as sativa may make you overly anxious use indica strains
No bone lesions no pain just tired but I am taking a lot of cannabis which explains the tiredness)Kidneys are stable and mspike is stable. I test my blood every two months.
My haematologist works with me and understands, I am trying to treat myself without doing any permanent damage to my body.
I had such bad neuropathy you could drop a concrete block on my feet and I would not feel it.
The cbd and thc has made my life very livable and has allowed me to recover from all of the side effects from chemo.
Don’t get me wrong chemo saved my life, the cbd and thc gave me my life back.
For me the most important thing is having a Doctor who understands me and my disease
And number one is my team of healthcare providers are all mm specialists.
As my Doctor keeps saying my prognosis from the start was for overall survival with stem cell transplant was 32 months.
I am now 50 months still have MM, but manageable have no other physical ailments. His words keep doing whatever you are doing as long as it’s working.
Thank you for your website it has been a tremendous aid for me in my journey

Reply
    David Emerson says 7 months ago

    Hi Robert-

    It sounds like you figured out the best of both conventional and non-conventional to manage your MM.

    Well done.

    David Emerson

    Reply
Joe Bonneville says 10 months ago

Curious as to the strain of CBD/THC you have found to be the most effective along with dosage and schedule

Reply
    David Emerson says 10 months ago

    Hi Joe-
    The studies I have read and cite in the guide do not specify either the strain nor dosing. The closest they get is stating that the important thing
    is to find a CBD oil with the highest percentage of cannabinoids as possible.

    Sorry I can’t be more specific.

    David Emerson

    Reply
Joyce Henderson says last year

How can I find out whats good for the health of the bones. The bones are my problem. What can I order to help or stop the degeneration of the bones?

Reply
Joyce Henderson says last year

What can I start doing now with Multiple Myeloma since 2028. I need something for my bones and sick of chemo

Reply
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Reply
Louise Naczek says last year

What mg. of CBD oil would I use?
I have had myeloma 8 years.
No SCT, no relapse.I have been on the cocktail RVD.
Always have intense pain in thighs.

Reply
Robyn Curtin says last year

My twin sister Paula was diagnosed with MM 2 months ago we live in Australia..which CBD product do you recommend (preferably organic)

Reply
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Armando cruz says 3 years ago

How much of a dosage per day of Cbd oil should we be taking for multiple mylenoma

Reply
    David Emerson says 3 years ago

    Hi Armando-

    None of the studies in the MM Cancer Coaching Cannabis guide state the recommended dose. The results are based on the longer and greater the administration of CBD the better the result.

    A more important metric is CBD oil use for MM is the amount of cannabidiol in the oil and the ratio of cannabidiol to THC. Studies show a 1:1 ratio is the most effect against MM.

    Studies show that many CBD brands often have only 1-5% of cannabinoids in the oil. Studies show that a MMer will benefit more from a percentage greater than 24%. The STRAIN is the key in this case.

    Let me know if you have any questions.

    thanks

    David Emerson

    Reply
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Brenda says 4 years ago

Hi just heard about CBD from a co-worker. I am the caregiver to my partner of 19 years. He has had MM for three years now and in the last month the plasma cells and other blood work started to get worse. He too was feeling worse. This past Saturday I rushed him to the ER with sepsis 10 days after a high does of a new Chemo treatment. He’s 73, nothing else wrong but MM and sadly he is bent over due to many fractures in his back. I’m looking to reach out to others on nutrition and more….caregiver overload.

Reply
    David Emerson says 4 years ago

    Hi Brenda-

    I am sorry to read of your partner’s situation. I will be direct with you as you are being direct with me. I believe that the 73 year old body must manage his/her toxicity very carefully. I have learned that oncologists overdo it. Yes, CBD is an integrative therapy meaning it enhances the efficacy of velcade.

    Further, there are a number of evidence-based “integrative” therapies for conventional MM chemotherapies such as velcade, revlimid, melphalan, others. Yes, there are foods that are also anti-MM.

    I am both a MM survivor and MM cancer coach.

    David Emerson

    Reply
What is Myeloma Cancer? says 5 years ago

[…] has probably told you that myeloma is incurable but very treatable. You may be wondering what “very treatable” means. Yes, there is a long and growing list of FDA approved chemotherapy regimens for MM. It is […]

Reply
deb says 5 years ago

I am wondering if the CBD oil must have THC in it to be effective vs cancer?
debbie

Reply
    David Emerson says 5 years ago

    Hi Deb-

    The study that you came in on explains that CBD alone enhances Velcade. Each study I have read (for different cancers) usually specify whether they are testing Cannabinoids without THC or with THC. The study linked below talks about this very issue-

    Br J Clin Pharmacol. 2013 Feb;75(2):303-12. doi: 10.1111/j.1365-2125.2012.04298.x.
    Cannabidiol as potential anticancer drug.

    What cancer have you been diagnosed with? What stage?

    David Emerson

    Reply
Nora Brown says 5 years ago

I am curious as to how studies are completed with CBD when it is basically illelgal???

Reply
    David Emerson says 5 years ago

    Hi Nora-

    Several things. I am not an expert but as I understand it, CBD is illegal at the Federal level in the U.S. The FED govt has stated that if a state legalizes CBD for medical use they they, the FED gov’t will not prosecute that state.

    More importantly, many of the studies that I have read have been conducted in other countries. The Pubmed study linked below is an example. “B J Clin Pharmacol.” stands for British Journal of Clinical Pharmacology.

    Br J Clin Pharmacol. 2013 Feb;75(2):303-12. doi: 10.1111/j.1365-2125.2012.04298.x.

    Cannabidiol as potential anticancer drug.

    Having said all that I have to say that the gov’t’s attitude toward CBD is slowing the research of CBD as cancer therapy.

    David Emerson

    Reply
Donald King says 5 years ago

How do you take CBD?

Reply
    David Emerson says 5 years ago

    Hi Don-

    I am a long-term MM survivor. I am not currently undergoing Velcade therapy. CBD enhances Velcade. I am not taking CBD.

    Have you been diagnosed with multiple myeloma? If so, what stage? Any symptoms such as bone pain, anemia or kidney damage?

    David Emerson

    Reply
      DIANE BOAL says 5 years ago

      Hello, Is there a certain type of cannabidiol to use for multiple myeloma?
      Diane

      Reply
        David Emerson says 5 years ago

        Hi Diane-

        It is less about a brand name for the CBD oil for MM and more about the ratio of CBD to THC and dosing instructions. I am assuming that you are talking about CBD that is cytotoxic to MM as opposed to managing cancer pain and or nausea.

        David Emerson

        Reply
nora says 5 years ago

WAY TO GO, DAVE!!!

Reply
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