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Multiple Myeloma- Stem Cell Transplant- Harvest Tips

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Stimulating Your Body’s Production of Stem Cells in Preparation for an Autologous Stem Cell Transplant (ASCT)? Try these Non-Toxic Therapies-

The standard-of-care for healthy newly diagnosed multiple myeloma (MM) patients is to have induction chemotherapy followed by an autologous stem cell transplant (ASCT). As the forum post from The Myeloma Beacon indicates, it is not uncommon for newly diagnosed multiple myeloma patient to have difficulty harvesting enough stem cells needed for their ASCT. HBOT may be the answer…

The advice given by conventional oncology is to have more toxic chemotherapy and maybe this will help the patient produce more stem cells.

I was diagnosed with multiple myeloma in early 1994. I underwent my induction therapy in the Spring of 1995 and Dr. Berger, my oncologist, prescribed two rounds of cytoxan chemotherapy to stimulate my body’s production of stem cells.

Hindsight is 20/20 of course but cytoxan (cyclophosphamide) is highly toxic. I developed several short, long-term and late stage side effects from my two cycles of cytoxan. My mantra “If I knew then what I know now…” applies to my cytoxan chemotherapy as well as much of my conventional therapy in 1994, ’95 and ’96.

man hand holding his nutritional supplemets, healthy lifestyle background.

Rather than the two cycles of cytoxan I wish I had undergone HyperBaric Oxygen Therapy (HBOT) while taking B-complex supplements.

Two articles linked and excerpted below cite healthy therapies for increasing the body’s ability to produce stem cells.

What have I learned about MM over the past 20+ years? Myeloma is about two things

  1. symptoms (bone damage, anemia, kidney function, etc.) and
  2. side effects from toxic chemotherapy.

Whether you are debating treatment options, currently undergoing treatment and experiencing painful treatment-related side effects, or trying to figure out how to stay in remission, I want to share what I’ve learned from 22 years of full remission from Multiple Myeloma.

David Emerson

  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:

Difficulty harvesting stem cells

“No stem cells after two days of apheresis. After time (six weeks), tried again with single dose of etoposide followed by GCSF for 13 days. Insufficient peripheral stem cells to even try apheresis or Mozobil…”

Stem cell mobilization by hyperbaric oxygen.

“We hypothesized that exposure to hyperbaric oxygen (HBO(2)) would mobilize stem/progenitor cells from the bone marrow by a nitric oxide (*NO) -dependent mechanism.

Stem cell mobilization did not occur in knockout mice lacking genes for endothelial *NO synthase. Moreover, pretreatment of wild-type mice with a *NO synthase inhibitor prevented the HBO(2)-induced elevation in stem cell factor and circulating stem cells. We conclude that HBO(2) mobilizes stem/progenitor cells by stimulating *NO synthesis.

Study shows a new role for B-complex vitamins in promoting stem cell proliferation

“Folates can stimulate stem cell proliferation independently of their role as vitamins, according to a new study that used an in vitro culture and animal model system in their findings. Folates, whether supplemental B vitamins or natural folates found in food, are essential for the proper functioning of all cells in the body and are critical to prevent birth defects…”


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Fun Stem Cell Collection for Multiple Myeloma? Viagra? Wait, What??? - PeopleBeatingCancer says 3 years ago

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