Cannabinoids as Non-Toxic Anti-Angiogenic Myeloma Therapy?

“Tumors need a blood supply to grow so they require new blood vessels. The native blood supply is insufficient, so angiogenesis is stimulated by the cancer itself for its own growth.”

The article linked and excerpted below quotes several oncologists making the case for anti-angiogenic chemotherapy drugs such as bevacizumab (Avastin),sorafenib (Nexavar®),and sunitinib (Sutent®)- all angiogenesis inhibitors. Admittedly, these drugs are expensive, cause side effects and will stop working eventually. What if your myeloma therapy was anti-angiogenic but non-toxic and inexpensive?

This idea isn’t radical or even that new. There is a great deal of research that establishes the anti-angiogenic (and anti-myeloma) properties of both cannabinoids and curcumin for example. When I happened on Dr. Bill Li’s Ted Talk in 2010 a whole new world opened up to me.

Can We Eat To Starve Cancer?

Among other non-toxic anti-angiogenic myeloma therapy that I follow daily, weekly, etc. I supplement with Life Extension Super Bio-Curcumin and have been since about 2006.

And my incurable blood cancer has remained in complete remission in all that time. I chose to take LE Super Bio-Curcumin because of it’s efficacy as a myeloma therapy and because it has been evaluated and approved by Consumerlab.com, an independent testing organization.

I am both a myeloma survivor and MM cancer coach. If you have been diagnosed with multiple myeloma consider both conventional (FDA approved) and evidence-based non-conventional anti-angiogenic therapies.

Thank you,

David Emerson

MM Survivor
MM Cancer Coach
Director PeopleBeatingCancer

Cannabinoids[edit]

“According to a study published in the August 15, 2004 issue of the journal Cancer Research, cannabinoids, the active ingredients in marijuana, restrict the sprouting of blood vessels to gliomas (brain tumors) implanted under the skin of mice, by inhibiting the expression of genes needed for the production of vascular endothelial growth factor (VEGF).”

What Are Anti-Angiogenesis Drugs to Treat Cancer?

“Oncologists have a variety of medicines they can use to treat cancer. Each drug works in a different way, so doctors often give patients different types of drug at the same time to deliver a one-two blow to tumors. One type of drug used in metastatic cancer helps prevent the development of new blood vessels that feed tumors, a process called angiogenesis…

What Is Angiogenesis?

Angiogenesis is a normally balanced, biological process whereby our body develops new blood vessels as needed to deliver nutrients and oxygen and to eliminate metabolic waste and carbon dioxide. In cancer, however, tumors hijack this process for their own benefit.

“Angiogenesis happens during cancer formation, growth and – most importantly – spread,” says Dr. Davendra Sohal, an oncologist at the Cleveland Clinic. “Tumors need a blood supply to grow so they require new blood vessels. The native blood supply is insufficient, so angiogenesis is stimulated by the cancer itself for its own growth.”

Anti-angiogenesis medicines help control the process of new blood vessel development, Sohal says. They choke the blood supply to the cancer, preventing it from getting blood and nutrients…

[These drugs] don’t work for everyone,” Landau says. They work well in certain cancers, but not in others (for example, breast cancer). They can also wear off as time goes on. In the case of kidney cancers, Landau says, once you block one pathway for developing blood vessels, the tumor learns to develop others…

Chemotherapy and anti-angiogenesis drugs can’t cure metastatic cancer or prevent recurrence; they can only help prolong survival. “Cancer is a smart animal,” Sohal says. “It can find ways to fight back.” When patients develop resistance to chemotherapy, it’s time to change to a different chemotherapy drug, he says. “We’ll continue to use angiogenesis drugs as long as we have another chemotherapy option. However, by themselves, anti-angiogenesis drugs don’t do a whole lot.”

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Cannabinoids as Non-Toxic Anti-Angiogenic Myeloma Therapy?

“Tumors need a blood supply to grow so they require new blood vessels. The native blood supply is insufficient, so angiogenesis is stimulated by the cancer itself for its own growth.”

Recommended Reading:

Cannabinoids[edit]

What Are Anti-Angiogenesis Drugs to Treat Cancer?

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