Learn how you can stall the development of full-blown Multiple Myeloma with evidence-based nutritional and supplementation therapies.
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I had an IFE test (immunofixation electrophoresis) which showed elevated IgG at 2585. IgA & IgM were within normal range. Bone marrow biopsy test & Bence Jones test were done also. Bone marrow shows Kappa-Clonal plasma cells at 5%.
The 24-hour urine test shows no monoclonal proteins. My diagnosis is MGUS. Kappa light chain free is 29.7 (3.3-19.4) & Kappa/Lambda ratio is 2.52 (0.26-1.65). Red blood hemoglobin & hematocrit at very low end of normal range.
What supplements should I be taking to prevent full-blown myeloma Anything that has worked for you or someone else would be welcome. I am 84 years old & in good health otherwise.)
Thank you & God bless you, Rich
I’m sorry you’ve had trouble reaching me. Based on my experience you are low even for pre-myeloma or MGUS. Technically you are IGG kappa but again, very early.
At 83 and in otherwise good health I will guess that any slight MM is low risk and slow moving. I work with 93-year-old MGUS patient who has managed to keep his m-spike under one by supplementing with curcumin.
I think Mort takes one capsule daily (400 mg), maybe one in the am and one in the pm. Life Extension Super Bio-Curcumin
Adding anti-angiogenic foods and curcumin to your daily diet is an evidence-based but non-toxic way to reduce your risk of a MM diagnosis.
Let me know if you have any other questions.
Hang in there,
“Multiple myeloma (MM) evolves through a spectrum of disease from a premalignant stage of monoclonal gammopathy of undetermined significance (MGUS)
to an intermediate stage of smoldering multiple myeloma (SMM)
and finally presents with symptoms and signs of end-organ damage which leads to the diagnosis of MM . Studies indicate that almost all cases of MM are preceded by the precursor state of MGUS or SMM …
Based on its antimyeloma cell activity, we have performed a number of studies with curcumin in MGUS/SMM patients, including a randomised, double-blind placebo- controlled cross-over study, published in the American Journal of Hematology  where we showed that treatment of MGUS/SMM patients with curcumin resulted in an improvement in markers of disease progression (i.e., free light-chain ratio (rFLC), paraprotein levels, percentage plasma cells) in some patients .
A number of patients who participated in our studies and who showed a benefit, have continued to take curcumin over a number of years, of their own volition, even though the studies in which they were participating are complete…”
“As tumors grow, they often build blood vessels that connect to the body’s circulatory system. The vessels provide conduit for nutrients that tumors need to continue their expansion. Drugs that block the process of blood-vessel creation, known as angiogenesis, have been approved to treat certain types of colon, lung, and breast tumors, as well as other cancers.
Research suggests that compounds found in certain foods, such as green tea, red grapes, kale, and artichokes may also inhibit angiogenesis. But that doesn’t mean such foods are a substitute or replacement for prescribed therapies, according to Dana-Farber Cancer Institute nutritionist Stacy Kennedy, MPH, RD, CSO, LDN…
A healthy diet, such as the one Kennedy describes, can provide a range of benefits for cancer patients, potentially by helping to reduce inflammation and manage common side effects of treatment, such as constipation and fatigue. The possibility that some of these foods may also interfere with tumor angiogenesis could be an additional motivation for including them in one’s diet, but should not be a person’s sole motivation for eating a plant-heavy diet, Kennedy emphasizes.
Concrete answers to whether foods with angiogenic-blocking compounds can actually benefit patients may emerge from studies like one recently launched by Harvard University, in which investigators are exploring whether patients who respond better to treatment than expected have certain dietary, environmental, or attitudinal aspects in common…”