Recently Diagnosed or Relapsed? Stop Looking For a Miracle Cure, and Use Evidence-Based Therapies To Enhance Your Treatment and Prolong Your Remission
Multiple Myeloma an incurable disease, but I have spent the last 25 years in remission using a blend of conventional oncology and evidence-based nutrition, supplementation, and lifestyle therapies from peer-reviewed studies that your oncologist probably hasn't told you about.
Click the orange button to the right to learn more about what you can start doing today.
Multiple Myeloma- Black Seed Oil, TQ- Kill MM, Pro Bone, Kidney, Heart-
Our results show that TQ inhibited the proliferation of MM cells irrespective of their sensitivity to doxorubicin, melphalan or bortezomib… Daily dosing with 3% thymoquinone was successful in reducing blood pressure in healthy adults.”
Conventional oncology has become pretty good at putting newly diagnosed multiple myeloma patients into remission by using a variety of FDA approved toxic therapies. Most MM patients have never heard of thymoquinone.
The most serious of all side effects is an eventuality of all multiple myeloma patients- MDR aka multi-drug resistance.
The answer, in this survivor’s opinion anyway, is the judicious use of those nasty, both life threatening while at the same time, life saving, toxic therapies. When I say “judicious” I simply mean to employ those therapies efficiently. For example, an autologous stem cell transplant aka high-dose, aggressive chemotherapy is NOT an efficient use of chemo.
The less toxicity, the fewer side effects and the less likelihood of MDR. But you might be thinking “that’s easier said than done!” And you may have a point…
The solution to the “less is more” conundrum faced by all multiple myeloma patients and survivors are evidence-based but non-toxic therapies like thymoquinone (TQ) aka black seed oil .
The five studies linked and excerpted below explain how TQ is:
- cytotoxic to multiple myeloma
- overcomes the chemoresistence of MM while enhancing chemotherapy regimens such as Velcade and Revlimid
- protected kidneys from the toxic effect of chemotherapy
- enhanced bone formation
- enhanced heart health
Keep in mind that TQ is a non-conventional therapy meaning the studies below are animal studies. Conventional oncology usually takes a different view of evidence-based non-conventional therapies such as TQ, curcumin, omega-3 fatty acids, etc. than I do.
However, it is important to understand that conventional oncology can’t cure multiple myeloma. So keep your options open.
If you have any questions, scroll down the page, post a question or comment and I will reply to you ASAP.
Thank you,
David Emerson
- MM Survivor
- MM Cancer Coach
- Director PeopleBeatingCancer
Recommended Reading:
- Can Multiple Myeloma Survivors Drink Red Wine???
- Bortezomib (Velcade) Resistance in Multiple Myeloma
- Early Stage Multiple Myeloma Diagnosis- Resveratrol? Pre-Habilitation?
Thymoquinone
Thymoquinone is a phytochemical compound found in the plant Nigella sativa. It is also found in select cultivated Monarda fistulosa plants grown in the U.S. and steam distilled producing an essential oil.
In laboratory experiments in cells and in animals, it has shown antiinflammatory and antioxidant effects, and has been studied in models of cardiovascular diseases and diabetes,[1] neurodegenerative diseases and stroke,[2] and cancer.[3] A 2016 study suggests thymoquinone may have opioid tolerance-reduction effects.[4]…”
Thymoquinone Overcomes Chemoresistance and Enhances the Anticancer Effects of Bortezomib Through Abrogation of NF-κB Regulated Gene Products in Multiple Myeloma Xenograft Mouse Model
“Multiple myeloma (MM) is a B cell malignancy characterized by clonal proliferation of plasma cells in the bone marrow. With the advent of novel targeted agents, the median survival rate has increased to 5 -7 years.
However, majority of patients with myeloma suffer relapse or develop chemoresistance to existing therapeutic agents. Thus, there is a need to develop novel alternative therapies for the treatment of MM.
Our results show that TQ inhibited the proliferation of MM cells irrespective of their sensitivity to doxorubicin, melphalan or bortezomib.
Interestingly, TQ treatment also resulted in a significant inhibition in the proliferation of CD138+ cells isolated from MM patient samples in a concentration dependent manner. TQ also potentiated the apoptotic effects of bortezomib in various MM cell lines through the activation of caspase-3, resulting in the cleavage of PARP…
Overall, our results demonstrate that TQ can enhance the anticancer activity of bortezomib in vitro and in vivo and may have a substantial potential in the treatment of MM.”
Thymoquinone Supplementation and Its Effect on Kidney Tubule Epithelial Cells in Vitro
“Reactive oxygen species (ROS) play a major role in the progression of renal disease. Vitamins can be used to attenuate the production of ROS and potentially slow or stop the progression of renal disease…
Thymoquinone has been documented to have a cytocidal effect on cancer cells and reduced the cytotoxicity of standard antineoplastic drugs.
Thymoquinone has also been documented to protect renal tissue by significantly reducing the side effect of nephrotoxicity associated with various medications. The hepatoprotective property of thymoquinone may be attributed to the preservation of intracellular glutathione or may be related to the inhibition of thromboxane B2 production.
The overall goal of this study was to define a dose of TQ which will increase cellular glutathione levels without cytotoxic effects.
Data obtained suggests that: (1) TQ does not act as a prooxidant at higher concentrations, which would induce cellular damage leading to cell death, and (2) at 72 hours in culture there was a significant increase in glutathione levels in all treatment groups when compared with control cells suggesting possible protective effects of this compound…”
Thymoquinone Accelerates New Bone Formation in the Rapid Maxillary Expansion Procedure
“Objective: The aim of this study was to evaluate the effect of systemic thymoquinone (TQ) in a rat rapid maxillary expansion (RME) study…
Results: New bone formation, number of capillaries and the ratio of intensities of inflammatory cells in maxillary sutures was higher in the TQ groups than in the other groups. Statistical analysis also demonstrated that osteoblast and osteoclast numbers were also highest in the TQ1 group.
Conclusion: Histomorphometric analysis demonstrated that systemic use of thymoquinone may be effective in accelerating new bone formation in the RME procedure and that TQ may be beneficial in preventing relapse following the RME procedure…”
Effects of Standardized Black Seed Oil Cold Press Supplement Over A Six Week Period on Blood Pressure and Heart Rate in Healthy Patients: A Nonrandomized Clinical Trial
“Hypertension can increase the risk of cardiovascular diseases including coronary artery disease, stroke, heart failure and others [2,3]..
Thymoquinone (TQN) is one of the main components of the essential oil extracted from black cumin seeds of N. sativa making up to 48% [7]. This component was found to be beneficial in a myriad of pathologies including cancer [8], inflammatory disorders [9], pain [10], diabetes [11], hypertension [12] and more.
The protective effect of TQN can be attributed to its ability to mitigate oxidative stress and inflammation through various mechanisms [13,14]…
Black Seed Oil- ThymoQuin contains 15 mg Thymoquinone extracted from black seed oil. Administration was in the form of liquid capsules (BCC002) manufactured by Nature’s Value Inc-
Subjects were given a daily dose of 500 mg ThymoQuin containing 15 mg (Thymoquinone) in the form of capsules for 42 days…
Results: Twenty patients received 500mg daily of ThymoQuin™ (3% thymoquinone) for six weeks. A significant decrease in blood pressure and an increase in heart rate could be observed. Following the washout period and placebo treatment, blood pressure was slightly increased and the treatment effects started diminishing.
Conclusion: Daily dosing with 3% thymoquinone was successful in reducing blood pressure in healthy adults.”
Thymoquinone Protects against Myocardial Ischemic Injury by Mitigating Oxidative Stress and Inflammation
“Conclusion- Based on our present findings, it can be concluded that TQ exhibits its cardioprotective effects by enhancing antioxidant defense, inhibiting lipid peroxidation, and inflammation as well as preserving the cardiomyocytes, which all together may translate into the functional recovery of heart function…”
