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Ultrasound-Curcumin kills cervical cancer

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The results showed enhanced necrosis in cervical cancer cell lines after combined treatment and confirmed the ultrasound capacity to increase effectiveness of curcumin.

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The study linked and excerpted below is an excellent example of integrative therapy. Evidence-based research supporting ultrasound enhancing a well-studied, non-toxic, inexpensive therapy to kill cervical cancer.

As a long-term survivor of an incurable cancer I understand the benefits of curcumin. Many multiple myeloma patients like me have been taking curcumin for years now. Numerous studies cite curcumin ability to kill MM cells too. With or without chemotherapy. But studies confirm curcumin’s ability to enhance the efficacy of certain chemotherapy regimens.

I take Life Extension’s Super Bio-curcumin. Studies show that this formulation of curcumin is more bioavailable than all other formulations of curcumin. Super Bio-Curcumin is well- reviewed on Amazon and is available through Amazon Prime (which I also recommend).

Please read the study below, order LE Super Bio-Curcumin and begin supplementing before you begin your ultrasound treatments. Start killing your cervical cancer immediately.

For more information about integrative therapies and cervical cancer, scroll down the page, post a question or comment and I will reply ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Therapeutic role of curcumin and its novel formulations in gynecological cancers

“Gynecological cancers are among the leading causes of cancer-associated mortality worldwide. While the number of cases are rising, current therapeutic approaches are not efficient enough. There are considerable side-effects as well as treatment resistant types.

In addition, which all make the treatment complicated for afflicted cases. Therefore, in order to improve efficacy of the treatment process and patients’ quality of life, searching for novel adjuvant treatments is highly warranted.

Curcumin, a promising natural compound, is endowed with numerous therapeutic potentials including significant anticancer effects. Recently, various investigations have demonstrated the anticancer effects of curcumin and its novel analogues on gynecological cancers. Moreover, novel formulations of curcumin have resulted in further propitious effects. This review discusses these studies and highlights the possible underlying mechanisms of the observed effects…”

Combined ultrasound-curcumin treatment of human cervical cancer cells

“Objectives-Human papillomavirus (HPV) is associated with cervical cancer. Studies showed curcumin inhibits HPV oncogenes expression but curcumin has low bioavailability. The objectives were: (1) to study ultrasound enhancement of curcumin effects on HeLa, SiHa and C33A, (2) to compare two frequencies for sonoporation and (3) to detect cell-free DNA released by the treatment…

Results- Combined curcumin ultrasound resulted in 9-, 12- and 16-fold higher necrosis in HeLa, SiHa and C33A cells respectively. Increased necrosis correlated with higher ultrasound frequencies. There was increased apoptosis in HeLa or SiHa cells with the combined treatment. Curcumin alone resulted in a lesser 2–4-fold increase in necrosis in the groups. Cell-free DNA was detected in the spent media of HeLa and SiHa but not C33A cultures…

Conclusions- The results showed enhanced necrosis in cervical carcinoma cell lines after combined treatment and confirmed the ultrasound capacity to increase effectiveness of curcumin. Cancer cells were smaller post-treatment suggesting microtubule structural disruption. Cell-free DNA was low molecular weight consistent with lysed host cell.”

Curcumin Nanoformulation for Cervical Cancer Treatment

“Cervical cancer is one of the most common cancers among women worldwide. Current standards of care for cervical cancer includes surgery, radiation, and chemotherapy. Conventional chemotherapy fails to elicit therapeutic responses and causes severe systemic toxicity.

Thus, developing a natural product based, safe treatment modality would be a highly viable option.

Curcumin (CUR) is a well-known natural compound, which exhibits excellent anti-cancer potential by regulating many proliferative, oncogenic, and chemo-resistance associated genes/proteins. However, due to rapid degradation and poor bioavailability, its translational and clinical use has been limited.

To improve these clinically relevant parameters, we report a poly(lactic-co-glycolic acid) based curcumin nanoparticle formulation (Nano-CUR). This study demonstrates that in comparison to free CUR, Nano-CUR effectively inhibits cell growth, induces apoptosis, and arrests the cell cycle in cervical cancer cell lines. Nano-CUR treatment modulated entities such as miRNAs, transcription factors, and proteins associated with carcinogenesis. Moreover, Nano-CUR effectively reduced the tumor burden in a pre-clinical orthotopic mouse model of cervical cancer by decreasing oncogenic miRNA-21, suppressing nuclear β-catenin, and abrogating expression of E6/E7 HPV oncoproteins including smoking compound benzo[a]pyrene (BaP) induced E6/E7 and IL-6 expression.

These superior pre-clinical data suggest that Nano-CUR may be an effective therapeutic modality for cervical cancer.”

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The Most BioAvailable Curcumin Formulas - PeopleBeatingCancer says last year

[…] Ultrasound-Curcumin treatment kills cervical cancer […]

Kaye Johnson says 4 years ago

Thank you so much for sharing this information! My best childhood friend is suffering from cervical cancer and I’m also suffering myself by seeing her like this.

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