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Vitamin D status and Colorectal Cancer Survival

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Conclusion- Higher predicted 25(OH)D levels after a diagnosis of colorectal cancer (CC) may be associated with improved survival.

Study after study finds the same finding. Blood levels of vitamin D3 predicts a longer survival in cancer patients. The study below is focusing on colorectal cancer patients but the study could just as easily be talking about my cancer, multiple myeloma. And incurable blood cancer.

Keep in mind that I am talking about serum blood levels, meaning the amount of vitamin D3 in your blood stream. I get a blood test annually from a local LabCorp location. I take 1000 mg x 3 daily of vitamin D. I read about cancer survivors taking more and some taking less. The point is to have your blood checked regularly.

 I am both a cancer survivor and cancer coach. Surviving cancer is not about conventional (FDA approved) or non-conventional therapies. Surviving cancer is about using those therapies that work for you.

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Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer.

BACKGROUND: In an earlier study, a 25-hydroxyvitamin D(3) (25(OH)D) score calculated from known predictors of vitamin D status significantly predicted plasma levels of 25(OH)D and the risk of colorectal cancer, but the influence of the 25(OH)D score on survival after diagnosis is unknown.

MATERIALS AND METHODS: We prospectively examined the influence of post-diagnosis predicted 25(OH)D levels on mortality among 1017 participants in the Nurses’ Health Study and Health Professionals Follow-Up Study who were diagnosed with colorectal cancer from 1986 to 2004. Colorectal cancer-specific and overall mortality according to quintiles of predicted 25(OH)D levels were assessed. Cox proportional hazards models were used to calculate hazard ratios (HRs) adjusted for other risk factors of survival.

RESULTS: Higher predicted 25(OH)D levels were associated with a significant reduction in colorectal cancer-specific (P trend=0.02) and overall mortality (P trend=0.002). Compared with levels in the lowest quintile, participants with predicted 25(OH)D levels in the highest quintile had an adjusted HR of 0.50 (95% CI, 0.26-0.95) for cancer-specific mortality and 0.62 (95% CI, 0.42-0.93) for overall mortality.

Conclusion- Higher predicted 25(OH)D levels after a diagnosis of colorectal cancer may be associated with improved survival. Further study of the vitamin D pathway in colorectal cancer is warranted.

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