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Integrative Therapies Can Enhance the Efficacy of Conventional Lung Cancer (LC) Chemotherapy while Reducing the Risk Of Side Effects
The newly diagnosed lung cancer patient has several challenges facing him/her. It is common knowledge that LC is one of the most aggressive cancers with dismal five-year survival rate. But it is important to dig into why five -year LC survival rates are so dismal. In short:
LC patients undergoing chemotherapy face multi-drug resistance (MDR)
To learn more about evidence-based therapies for lung cancer, please watch the short video below:
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Curcumin extracted from the rhizomes of Curcuma longa L. has been shown to have inhibitory effects on cancers through its anti-proliferative and pro-apoptotic activities.
Emerging evidence demonstrates that curcumin can overcome drug resistance to classical chemotherapies.
In our study, we first demonstrated that curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells.”
” In summary, our results demonstrated, for the first time, the elevation of miR-210 by EGCG in LC cell lines and this is mediated by the stabilization of HIF-1α. This event contributes to the anticancer activity of EGCG….”
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