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Endometriosis Therapy

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“The results of this clinical trial show that administration of antioxidants reduces chronic pelvic pain in women with endometriosis (endo) and inflammatory markers in the peritoneal fluid…”

Endometriosis (endo) is an often painful disorder in which tissue similar to the tissue that normally lines the inside of your uterus — the endometrium — grows outside your uterus.

The studies linked and excerpted below do not represent hand’s down proof that endo can be treated with non-conventional therapies. I am not talking about curing anything. I am blogging about evidence-based, inexpensive therapies than may be able to reduce endo pain without toxicity and/or side effects.

I am a long-term cancer survivor and cancer coach. I learned about non-toxic therapies like curcumin and resveritrol years ago. I have supplemented myself with both curcumin and resveritrol  since 2006 and I have remained in complete remission from my “incurable” cancer since 1999. My point is that these two therapies in particular and antioxidants in general treat a host of chronic diseases and do so inexpensively while causing no side effects.

I take Life Extension Super Bio-Curcumin as this formula has been shown to be much more bioavailable (absorbable) and conventional curcumin and has been tested and approved by Consumerlab.com, an independent testing service.

Please scroll down the page to post a question or comment. I will answer you ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

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Endometriosis and endometriosis-associated cancers: new insights into the molecular mechanisms of ovarian cancer development

“Endometriosis is a fascinating disease that we strive to better understand. Molecular techniques are shedding new light on many important aspects of this disease: from pathogenesis to the recognition of distinct disease variants like deep infiltrating endometriosis.

The observation that endometriosis is a cancer precursor has now been strengthened with the knowledge that mutations that are present in endometriosis-associated cancers can be found in adjacent endometriosis lesions.

Recent genomic studies, placed in context, suggest that deep infiltrating endometriosis may represent a benign neoplasm that invades locally but rarely metastasises. Further research will help elucidate distinct aberrations which result in this phenotype. With respect to identifying those patients who may be at risk of developing endometriosis-associated cancers, a combination of molecular, pathological, and inheritance markers may define a high-risk group that might benefit from risk-reducing strategies…”

Curcumin inhibits endometriosis endometrial cells by reducing estradiol production

“Endo is a complex estrogen-dependent disease that is defined as the presence of endometrial gland and stroma outside the uterine cavity. Although the exact mechanism for the development of endo remains unclear, there is a large body of research data and circumstantial evidence that suggests a crucial role of estrogen in the establishment and maintenance of this disease…

This study is an attempt to assess the effect of curcumin on inhibiting endometriosis endometrial cells and to investigate whether such an effect is mediated by reducing estradiol production…

In summary, in this study we found that E2 is important in ectopic endometrium, and epithelial cell is in dominant position with E2 secretion. Curcumin was able to suppress the proliferation of endometrial cells by reducing the E2 value….”

Resveratrol successfully treats experimental endometriosis through modulation of oxidative stress and lipid peroxidation.

“The purpose of this study was to investigate the potential therapeutic efficiency of resveratrol in the treatment of experimental endometriosis in rats…

In a rat endometriosis model, resveratrol showed potential ameliorative effects on endometriotic implants probably due to its potent antioxidative properties….”

Antioxidant supplementation reduces endometriosis-related pelvic pain in humans.

“We previously suggested that women with endometriosis have increased oxidative stress in the peritoneal cavity. To assess whether antioxidant supplementation would ameliorate endometriosis-associated symptoms, we performed a randomized, placebo-controlled trial of antioxidant vitamins (vitamins E and C) in women with pelvic pain and endometriosis…

Our results indicated that after treatment with antioxidants, chronic pain (“everyday pain”) improved in 43% of patients in the antioxidant treatment group (P = 0.0055) compared with the placebo group. In the same group, dysmenorrhea (“pain associated with menstruation”) and dyspareunia (“pain with sex”) decreased in 37% and 24% patients, respectively. In the placebo group, dysmenorrhea-associated pain decreased in 4 patients and no change was seen in chronic pain or dyspareunia.

The results of this clinical trial show that administration of antioxidants reduces chronic pelvic pain in women with endometriosis and inflammatory markers in the peritoneal fluid…”

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