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Vaccines and “Out of the Box” Therapies for Brain Cancer

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“An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain cancer

Brain cancer (BC) can be difficult to treat if the patient or survivor thinks only about conventional (FDA approved) therapies. While surgical tumor reduction is almost always the first and best method to “debulk” a cancer, sometimes it’s impossible to cut out the tumor. The articles below cite vaccines for BCs- vaccines that function as a primary therapy or as an integrative therapy.

 

The challenge of the BC patient is to learn everything there is to know about brain cancer in the days and weeks following your diagnosis. A tall order to put it mildly.

I can help. I am both a long-term cancer survivor and cancer coach. Experience and research has taught me that patients diagnosed with incurable cancers must think outside the box when it comes to treating their cancer. Conventional, evidence-based non-conventional, integrative, complementary- patients must use every possible tool in the cancer therapy tool box.

For more information about all forms of evidence-based BC therapies, scroll down the page, post a question or comment and I will reply ASAP.

Thank you,

David Emerson

  • Cancer Survivor
  • Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:


Study: Vaccine targets malignant brain cancer antigens, significantly lengthens survival

“An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor…Median survival in a Phase I clinical trial at Cedars-Sinai’s Johnnie L. Cochran, Jr. Brain Tumor Center was 38.4 months, significantly longer than the typical 14.6-month survival of patients with newly diagnosed glioblastoma receiving standard therapy alone, which includes radiation and chemotherapy….”

‘A crack in the door’: Glimpses of hope for the future of brain cancer care

“There are more than 120 different types of brain tumors, afflicting nearly 700,000 people in the U.S. and killing nearly 17,000 every year, according to the American Brain Tumor Association. The Biden family didn’t disclose Beau’s type of brain cancer, but some have speculated it was likely a glioblastoma, a particularly aggressive type of brain tumor that is among the most common adult brain cancers…

Right now, the standard treatment for glioblastoma is a combination of surgery, radiation and chemotherapy. There are few options when those fail, but Holland is cautiously optimistic for the future. He believes with an as-yet-to-be-determined combination of immunotherapy and precision medicine, brain cancer researchers may finally make some headway against this long intractable problem…”


Vaccine as Brain Cancer Therapy

The day may soon come when surgery, chemo and radiation appear barbaric as brain cancer therapies- vaccines may become the new, effective standard-of-care 

If you have been diagnosed with brain cancer I have good news and I have bad news. First, the bad news. Conventional (FDA approved) oncology has little to offer you other than expensive chemo and radiation with a good chance of nasty collateral damage.

 

Now the good news. As the studies linked and excerpted below explain, vaccines may become the new, effective standard-of-care for brain cancer. The hitch is that this technology is constantly changing. A post I write today, July 24th, 2017, may be out-of-date by the time you read it.

I am both a cancer survivor and cancer coach. I work with cancer patients to research both conventional and non-conventional (vaccines…) therapies for their type and stage of cancer.

Survival in Patients with Glioblastoma Receiving Valganciclovir

“Here we present current retrospective data on 50 patients with glioblastoma who received valganciclovir as an add-on to standard therapy at Karolinska University Hospital as adjuvant treatment (Section S2 in the Supplementary Appendix). The rate of survival of treated patients was remarkably high: at 2 years, 62% were alive, as compared with 18% of contemporary controls with a similar disease stage, surgical-resection grade, and baseline treatment…”

Brain Cancer Vaccine Proves Effective, Study Suggests

“A new brain cancer vaccine tailored to individual patients by using material from their own tumors has proven effective in a multicenter phase 2 clinical trial at extending their lives by several months or longer. The patients suffered from recurrent glioblastoma multiforme…

Antiviral May Boost Survival in Brain Cancer

“Antiviral therapy against cytomegalovirus (CMV) — typically only thought a threat in immunosuppressed patients — was linked to dramatically improved survival in patients with glioblastoma, based on one center’s experience…The results were even better in the subgroup treated longer, up to 70% and 90% 2-year survival…”

Targeted therapy for glioblastoma multiforme neoplastic meningitis with intrathecal delivery of an oncolytic recombinant poliovirus.

CONCLUSION: These results suggest that intrathecal treatment with PVS-RIPO may be useful for treatment of neoplastic meningitis in patients with glioblastoma multiforme and provides a rationale for clinical trials in this area..”

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