C-B-D kills multiple myeloma and enhances Velcade

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These results showed that Cannabidiol by itself or in synergy with BORT strongly inhibited growth, arrested cell cycle progression and induced MM cells death…

Newly diagnosed myeloma patients are often told that their cancer is incurable but very treatable.”

Most newly diagnosed mmers find this statement to be confusing, bewildering and downright annoying. It has taken me every bit of the more than 20 years since my original myeloma diagnosis to understand what it means for a cancer to be incurable but treatable.

What have I learned about MM over the past 20+ years? Myeloma is about two things 1) symptoms (bone damage, anemia, kidney function, etc.) and 2) side effects from toxic chemotherapy.

MMers usually don’t die from their cancer. They die from health problems caused by their cancer such as bone damage and/or from the toxicity caused by chemotherapy and radiation.

The solution? Take an integrative approach to managing your multiple myeloma. Enhance the efficacy of chemotherapy and while you reduce the toxicity.

Based on the study linked below, cannabidiol and cannabis can work both on its own and with Velcade to induce cell death in Multiple Myeloma cells.  If you or a loved one have been diagnosed with Multiple Myeloma, let me say this loud and clear:

It is critical that you become an active participant in your care. Learn everything you can.

I am alive today largely because I took the time to find out everything I could about Multiple Myeloma and sought out the full spectrum of evidence-based MM therapies both conventional (FDA approved) and non-conventional.

Please watch the video below to learn more about the evidence-based, integrative therapies to combat treatment side effects and enhance your chemotherapy.

Click here to follow along with the Introduction Guide

Click here to get your FREE First Questions Guide


Your decision-making begins by learning about the full spectrum of evidence-based myeloma therapies, both conventional and non-conventional.  Here are some questions you may have right now:

  • Do Multiple Myeloma specialists know more about MM than regular oncologists? Yes.
  • What side effects should I expect from my induction chemotherapy? Prevention is key.
  • What do I do if I don’t reach complete remission? Don’t panic.
  • What therapies can I use that my oncologist won’t tell me about? Triplets are superior to doublets.
  • Does it matter if I wait to have an autologous stem cell transplant- No. Studies show there is no survival advantage either earlier or later. 

The PubMed study linked and excepted below cites the ability cannabidiol  to kill mm cells and increase the efficacy of Velcade (bortezomib).

I wish you all the best on your Multiple Myeloma journey.

Hang in there,
David Emerson
  • MM Survivor
  • MM Cancer Coach
  • Director PeopleBeatingCancer

Recommended Reading:


The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. A role for transient receptor potential vanilloid type-2.

“Because bortezomib (BORT) (Velcade) is commonly used in MM treatment, we investigated the effects of CBD and BORT in CD138+TRPV2- MM cells and in MM cell lines transfected with TRPV2 (CD138+TRPV2+).

These results showed that Cannabidiol by itself or in synergy with BORT strongly inhibited growth, arrested cell cycle progression and induced MM cells death by regulating the ERK, AKT and NF-κB pathways with major effects in TRPV2+ cells. These data provide a rationale for using CBD to increase the activity of proteasome inhibitors in MM.”

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